Articles | Volume 62, issue 1
https://doi.org/10.5194/aab-62-143-2019
https://doi.org/10.5194/aab-62-143-2019
Original study
 | 
02 Apr 2019
Original study |  | 02 Apr 2019

Linkage disequilibrium and within-breed genetic diversity in Iranian Zandi sheep

Seyed Mohammad Ghoreishifar, Hossein Moradi-Shahrbabak, Nahid Parna, Pourya Davoudi, and Majid Khansefid

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Cited articles

Al-Mamun, H. A., Clark, S., Kwan, P., and Gondro, C.: Genome-wide linkage disequilibrium and genetic diversity in five populations of Australian domestic sheep, Genet. Sel. Evol., 47, 90, https://doi.org/10.1186/s12711-015-0169-6, 2015. 
Barbato, M., Orozco-terWengel, P., Tapio, M., and Bruford, M. W.: SNeP: a tool to estimate trends in recent effective population size trajectories using genome-wide SNP data, Frontiers in genetics, 6, 109, https://doi.org/10.3389/fgene.2015.00109, 2015. 
Barrett, J. C., Fry, B., Maller, J., and Daly, M. J.: Haploview: analysis and visualization of LD and haplotype maps, Bioinformatics, 21, 263–265, 2004. 
Biegelmeyer, P., Gulias-Gomes, C. C., Caetano, A. R., Steibel, J. P., and Cardoso, F. F.: Linkage disequilibrium, persistence of phase and effective population size estimates in Hereford and Braford cattle, BMC Genet., 17, 32, https://doi.org/10.1186/s12863-016-0339-8, 2016. 
Bohmanova, J., Sargolzaei, M., and Schenkel, F. S.: Characteristics of linkage disequilibrium in North American Holsteins, BMC Genomics, 11, 421, https://doi.org/10.1186/1471-2164-11-421, 2010. 
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Short summary
Analysis of the genomic variation within a breed is an essential requirement for keeping the breed’s integrity and for defining proper breeding objectives. This research aimed to analyze the genomic structure of Iranian Zandi sheep and showed that a more dense marker is required to achieve genetic gain in Zandi sheep using genomic selection. Attention should be given to adopting an optimal mating system in order to avoid the further loss of genetic diversity in this breed.