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Archives Animal Breeding Archiv Tierzucht

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Logo Leibniz Institute for Farm Animal Biology Logo Leibniz Association
Arch. Anim. Breed., 61, 87-98, 2018
https://doi.org/10.5194/aab-61-87-2018
© Author(s) 2018. This work is distributed under
the Creative Commons Attribution 4.0 License.
Review
13 Feb 2018
Invited review: Genetic and genomic mouse models for livestock research
Danny Arends, Deike Hesse, and Gudrun A. Brockmann Albrecht Daniel Thaer-Institut für Agrar- und Gartenbauwissenschaften, Humboldt-Universität zu Berlin, 10115 Berlin, Germany
Abstract. Knowledge about the function and functioning of single or multiple interacting genes is of the utmost significance for understanding the organism as a whole and for accurate livestock improvement through genomic selection. This includes, but is not limited to, understanding the ontogenetic and environmentally driven regulation of gene action contributing to simple and complex traits. Genetically modified mice, in which the functions of single genes are annotated; mice with reduced genetic complexity; and simplified structured populations are tools to gain fundamental knowledge of inheritance patterns and whole system genetics and genomics. In this review, we briefly describe existing mouse resources and discuss their value for fundamental and applied research in livestock.

Citation: Arends, D., Hesse, D., and Brockmann, G. A.: Invited review: Genetic and genomic mouse models for livestock research, Arch. Anim. Breed., 61, 87-98, https://doi.org/10.5194/aab-61-87-2018, 2018.
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Short summary
In this invited review we discuss the value of mice in improving livestock breeding. This review gives an overview of currently available databases for mice that can be used in livestock genetics research. Furthermore, this paper describes how different mouse models have contributed to livestock research in the past.
In this invited review we discuss the value of mice in improving livestock breeding. This review...
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