Identification of a novel 24 bp insertion–deletion (indel) of the androgen receptor gene and its association with growth traits in four indigenous cattle breeds
Haidong Zhao,Mingli Wu,Shuhui Wang,Xiaohui Yu,Ze Li,Ruihua Dang,and Xiuzhu Sun
Haidong Zhao
College of Animal Science and Technology, Northwest A&F
University, Yangling, Shaanxi, 712100, P. R. China
Mingli Wu
College of Animal Science and Technology, Northwest A&F
University, Yangling, Shaanxi, 712100, P. R. China
Shuhui Wang
College of Animal Science and Technology, Northwest A&F
University, Yangling, Shaanxi, 712100, P. R. China
Xiaohui Yu
College of Animal Science and Technology, Northwest A&F
University, Yangling, Shaanxi, 712100, P. R. China
Ze Li
College of Animal Science and Technology, Northwest A&F
University, Yangling, Shaanxi, 712100, P. R. China
The androgen receptor (AR) plays the vital role of a bridge on the function of the androgen and has sexual size dimorphism. For this reason, the objective of this study was to explore the novel indel variants within the cattle AR gene and to detect a novel 24 bp indel within the AR gene. It significantly affected growth traits, suggesting that this indel may be a useful DNA marker for the elimination or selection of excellent individuals for cattle breeding.
The androgen receptor (AR) plays the vital role of a bridge on the function of the androgen and...