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AAB | Articles | Volume 61, issue 4
Arch. Anim. Breed., 61, 475-480, 2018
https://doi.org/10.5194/aab-61-475-2018
© Author(s) 2018. This work is distributed under
the Creative Commons Attribution 4.0 License.
Arch. Anim. Breed., 61, 475-480, 2018
https://doi.org/10.5194/aab-61-475-2018
© Author(s) 2018. This work is distributed under
the Creative Commons Attribution 4.0 License.

Original study 06 Dec 2018

Original study | 06 Dec 2018

Genetic characterization of some Turkish sheep breeds based on the sequencing of the Ovar-DRB1 gene in the major histocompatibility complex (MHC) gene region

Fulya Özdil et al.
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Cited articles  
Amills, M., Francino, O., and Sanchez, A.: A PCR-RFLP typing method for the caprine MHC class II DRB gene, Vet. Immunol. Immunop., 55, 255–260, 1996. 
Ballingall, K. T., Fardoe, K., and McKeever, D. J.: Genomic organisation and allelic diversity within coding and non-coding regions of the Ovar-DRB1 locus, Immunogenetics, 60, 95–103, 2008. 
Blattman, A. N., Hulme, D. J., Kinghorn, B. P., Woolaston, R. R., Gray, G. D., and Beh, K. J.: A search for associations between major histocompatibility complex restriction fragment length polymorphism bands and resistance to Haemonchus contortus infection in sheep, Anim. Genet., 24, 277–282, 1993. 
Bozkaya, F. and Kurar, E.: Linkage disequilibrium between MHC-linked microsatellite loci in White Karaman, Awassi and Merinolandschaf sheep breeds, F.Ü. Sağlık Bil. Derg., 19, 57–61, 2005. 
Brujeni, N. G. H., Emam, M., Mahmoudzadeh, H., Hamedmonfared, E., Talebnia Jahromi, R., and Rezaei, H.: Typing of Ovar-DRB1 second exon with PCR-RFLP technique in Iranian Shaul Sheep, Iran. J. Vet. Res., 10, 250–254, 2009. 
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Short summary
This study was conducted to identify the Ovar-DRB1 gene in the major histocompatibility (MHC) complex gene region by DNA sequencing in some native sheep breeds in Turkey. In total, 25 new alleles were revealed in Ovar-DRB1 in Turkish native sheep breeds, with 24 variable sites. The average pairwise genetic distance was 0.029 % for Ovar-DRB1. Two main groups were detected in Turkish sheep breeds. All Dağliç and Kivircik alleles and one allele from Karayaka, Malya and Sakiz are grouped together.
This study was conducted to identify the Ovar-DRB1 gene in the major histocompatibility (MHC)...
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