Exploration of the exonic variations of the iPSC-related Nanog gene and their effects on phenotypic traits in cattle
Meng Zhang,Chuanying Pan,Qin Lin,Shenrong Hu,Ruihua Dang,Chuzhao Lei,Hong Chen,and Xianyong Lan
Meng Zhang
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, 712100
Shaanxi, China
Chuanying Pan
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, 712100
Shaanxi, China
Qin Lin
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, 712100
Shaanxi, China
Shenrong Hu
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, 712100
Shaanxi, China
Ruihua Dang
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, 712100
Shaanxi, China
Chuzhao Lei
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, 712100
Shaanxi, China
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, 712100
Shaanxi, China
College of Animal Science and Technology, Northwest A&F University,
Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, 712100
Shaanxi, China
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Nanog is an important pluripotent transcription regulator, and its overexpression leads to a high expression of the growth and differentiation factor 3, affecting animal growth traits. The aim of this study was to explore the genetic variations within the Nanog gene and their effects on phenotypic traits in cattle. Six novel exonic single nucleotide polymorphisms were found in six cattle breeds and indicated that Nanog could be a candidate gene for marker-assisted selection in cattle breeding.
Nanog is an important pluripotent transcription regulator, and its overexpression leads to a...
